In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA-seq), delved into the contribution of synovial/tendon sheath progenitor cells to heterotopic bone formation.
Early on, every stem cell faces a fateful choice. During skin development, for instance, the embryonic epidermis begins as a single layer of epidermal progenitor cells.
New research appearing in the journal Nature Biotechnology answers important questions about the viability of treatments that seek to replace diseased and aged cells in the central nervous system with healthy ones.