Data today showed there are now four days worth of O negative blood in England - compared to two days last week. The health service aims to have more than six days of stocks.
The NHS Blood and Transplant unit are frantically trying to hire new donor carers who work alongside trained nurses to conduct health checks and support volunteers.
Professor Ian Roberts, an epidemiologist at the London School of Hygiene and Tropical Medicine, told MailOnline tranexamic acid could be a major part of the solution to England s blood shortage.
More than 10,000 appointments to donate blood over the next few weeks were booked over the last 24 hours in England. Most appointments this week are now fully booked.
Kind-hearted would-be blood donors in England have been left in half-an-hour queues because of the rush to give blood. Health chiefs issued an amber alert because of dwindling stocks.