Chinese scientists have successfully grown humanized kidneys inside pig embryos, marking a significant milestone for organ transplantation. Breakthrough in xenotransplantation: Detailed in a study published in journal Cell Stem Cell on Sept. 7, the remarkable achievement represents the first time a solid humanized organ has been cultivated within another species, offering a potential solution to the critical shortage of donor organs for transplantation. The researchers, led by Liangxue Lai from the Guangzhou Institutes of Biomedicine and Health in China, reportedly took five years to overcome the challenges of interspecies organ generation.
how long he may have two live. we ve never done this in a human, and i like to think that we have given him a better option than what continuing his therapy would have been. but whether it s a day, week, month, year, i don t know. the science involved gene editing pig embryos. four pig genes were deactivated, knocked out. this included one to stop the heart from growing too large once transplanted. six human genes were added to try to prevent the immune system from immediately rejecting it. the gene altered embryo was then transferred into a sow, with the subsequent litter grown for potential human transplant. i visited research farms in the us breeding gene edited pigs. the hope is, they could solve the organ donor shortage. in the uk, around 500
with his surgeon. he s said to be doing well, although it s unclear how long his new heart will last. we ve never done this in a human, and i like to think that we have given him a better option than what continuing his therapy would have been. but whether it s a day, week, month, year, i don t know. the science involved gene editing pig embryos. four pig genes were deactivated, knocked out. this included one to stop the heart from growing too large once transplanted. six human genes were added to try to prevent the immune system from immediately rejecting it. the gene altered embryo was then transferred into a sow, with the subsequent litter grown for potential human transplant. i visited research farms in the us breeding gene edited pigs. the hope is, they could solve the organ donor shortage. in the uk, around 500
month, year, i don t know. the science involved gene editing pig embryos. four pig genes were deactivated, knocked out. this included one to stop the heart from growing too large once transplanted. six human genes were added to try to prevent the immune system from immediately rejecting it. the gene altered embryo was then transferred into a sow, with the subsequent litter grown for potential human transplant. i visited research farms in the us breeding gene edited pigs. the hope is, they could solve the organ donor shortage. in the uk, around 500 patients die each year while on the transplant waiting list. some will object to animals being bred as spare parts, but the number needed would be dwarfed by the millions bred for meat. fergus walsh, bbc news.
therapy would have been. but whether it s a day, week, month, year, i don t know. the science involved gene editing pig embryos. four pig genes were deactivated, knocked out. this included one to stop the heart from growing too large once transplanted. six human genes were added to try to prevent the immune system from immediately rejecting it. the gene altered embryo was then transferred into a sow, with the subsequent litter grown for potential human transplant. i visited research farms in the us breeding gene edited pigs. the hope is, they could solve the organ donor shortage. in the uk, around 500 patients die each year while on the transplant waiting list. some will object to animals being bred as spare parts, but the number needed would be dwarfed by the millions