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UK launch for progressive multiple sclerosis mega-trial

UK launch for progressive multiple sclerosis mega-trial 7th May 2021 The MS Society had announced that a world-first mega-trial for progressive multiple sclerosis (MS) will be launched in the UK later this year. According to the charity, Octopus (named for its many arms) is “a revolutionary clinical trial that will transform the way treatments for progressive MS are tested – and could deliver desperately needed new options up to three times faster”. Octopus will test several drugs – as opposed to just one – against a placebo at the same time, and will also combine what would normally be two consecutive trial phases into one, potentially rapidly speeding up the development of new treatments.

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AI Identifies New Multiple Sclerosis Subtypes from Brain Scans

AI Identifies New Multiple Sclerosis Subtypes from Brain Scans In MS, the central nervous system is attacked, damaging the myelin covers of nerve cells. [© iceteastock - Fotolia.com] April 8, 2021 Scientists at University College London (UCL) have used artificial intelligence (AI) to identify three new multiple sclerosis (MS) subtypes from brain MRI scans. The researchers say the findings will help to identify those individuals with MS who are more likely to have disease progression, and could aid in more effective treatment targeting. Arman Eshaghi, MD, PhD, at UCL Queen Square Institute of Neurology, explained, “Currently MS is classified broadly into progressive and relapsing groups, which are based on patient symptoms; it does not directly rely on the underlying biology of the disease, and therefore cannot assist doctors in choosing the right treatment for the right patients. Here, we used artificial intelligence and asked the question: can AI find MS subtypes that follow a

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3 Distinct Subtypes of Multiple Sclerosis Have Been Identified in Brain Scans

3 Distinct Subtypes of Multiple Sclerosis Have Been Identified in Brain Scans 7 APRIL 2021 Symptoms might come and go. Speech could falter. There may be pain, or perhaps loss of senses. Almost certainly, though, a diagnosis of MS brings with itself a future full of uncertainty. Now, we have a new tool that might help to alleviate the latter.   Getting an accurate prognosis of MS early on can help people better prepare for what s to come, but clinical testing can t currently tell clinicians whether or not a specific case will respond well to a particular treatment in the future. A new study conducted by an international team of researchers used artificial intelligence to identify three relatively distinct subtypes of anatomy among brain scans taken from 6,322 patients with MS.

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