Study used a Mendelian randomization approach to identify REG1A and REG1B as potential biomarkers for early detection of pancreatic cancer, showing their causal effects and significance in cancer screening.
Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.
HUNTSVILLE, Ala., Sept. 20, 2022 /PRNewswire/ Discovery Life Sciences (Discovery), the Biospecimen and Biomarker Specialists, has entered into an agreement with Olink Holding AB (publ) (Olink)
2Programa de Salud Familiar Comunitaria e Intercultural, Ministerio de Salud Bolivia, La Paz, Bolivia
3Hydrosciences Montpellier, Université de Montpellier, Institut de Recherche pour le Développement, Centre National de la Recherche Scientifique, Montpellier, France
4Genetics Institute, Universidad Mayor de San Andrés, La Paz, Bolivia
Indigenous people living in the Bolivian Andes are exposed through their drinking water to inorganic arsenic, a potent carcinogen. However, the health consequences of arsenic exposure in this region are unknown. The aim of this study was to evaluate associations between arsenic exposure and changes in cancer-related proteins in indigenous women (
n = 176) from communities around the Andean Lake Poopó, Bolivia. Arsenic exposure was assessed in whole blood (B-As) and urine (as the sum of arsenic metabolites, U-As) by inductively coupled plasma-mass spectrometry (ICP-MS). Cancer-related proteins (