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Study reveals heart failure insights at single-cell level

Researchers examined the cell-intrinsic effects of hematopoietic stem cells with somatic mutations in circulating cells from heart failure patients. ....

Oxford Nanopore , Nature Cardiovascular Research , Heart Failure , Cardiovascular Disease , Ene Expression , Stem Cells ,

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated catalytically inactivated Cas9. ....

Cgis Cp , Research Square , Golden Gate Assembly , Golden Gate , Na Methylation , Ene Expression , Ibonucleic Acid ,