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Researchers unveil shared and unique brain molecular dysregulations in PTSD and depression

A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member of the Mass General Brigham health care system, working with colleagues at The University of Texas at Austin and Lieber Institute for Brain Development, uncovered both shared and distinct molecular changes across brain regions, genomic layers, cell types, and blood in individuals with post-traumatic stress disorder (PTSD) and major depressive disorder (MDD).

Texas
United-states
Kerry-ressler
Charlesb-nemeroff
Nikolaosp-daskalakis
Joel-kleinman
Clinical-sciences
Division-of-depression
Harvard-medical-school
Department-of-psychiatry
Lieber-institute-for-brain-development
Neurobiology-of-fear-laboratory-at-mclean-hospital

Breakthrough Study Sheds Light on Post-Traumatic Stress Disorder

The Psychiatric Genetics Consortium (PGC), a consortium of researchers led by scientists at University of California San Diego School of Medicine has made significant advancements in the understanding of the neurobiology of post-traumatic stress diso

Yale-university
Connecticut
United-states
Stanford-university
California
University-of-california-san-diego
San-diego
Mclean-hospital
Massachusetts
London
City-of
United-kingdom

Brain single-cell study reveals genes that may be involved in post-traumatic stress and major depressive disorders

Brain single-cell study reveals genes that may be involved in post-traumatic stress and major depressive disorders
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United-states
American
Nedh-kalin
Nikolaosp-daskalakis
Kerryj-ressler
Chris-chatzinakos
Division-of-depression
Translational-bioinformatics-laboratory-at-mclean-hospital
Mclean-hospital
American-journal
Translational-bioinformatics-laboratory
Anxiety-disorders

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