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New Treatment for Crohn s Disease In Children by Colleen Fleiss on February 20, 2021 at 11:32 PM
In children with Crohn s disease, nanotherapy reduces intestinal inflammation and shrinks lesions, said researchers.
According to the team, this approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. We injected into the intestinal lesion nanomolecules that carry an anti-inflammatory peptide, which is a tiny portion of a protein, said researcher Arun Sharma from Northwestern University in the US. The results were phenomenal. We saw reduction in inflammation based upon reductions in pro-inflammatory immune cells and proteins. The lesion size shrunk dramatically, which gives us hope that with this therapy we can salvage inflammatory tissue and avoid needing to surgically remove segments of the intestine in severe cases of Crohn s disease, Sharma added.