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Stem Cell Transplant Trumps Fingolimod for RRMS Relapse Risk

Autologous hematopoietic stem cell transplantation is linked to significantly lower relapse rates than fingolimod in patients with relapsing-remitting multiple sclerosis. But adverse events are common. ....

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Biogen to Pay $900M to Settle Physician Kickback Allegations

Former employee/whistleblower to receive $250 million as part of settlement involving three drugs used to treat muscular sclerosis. ....

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Ublituximab Bests Teriflunomide for MS in Two Phase 3 Trials

Ublituximab is superior to teriflunomide in suppressing multiple sclerosis relapses and lesions on MRI, suggest findings from the phase 3 ULTIMATE I and II trials. ....

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Novel Drug for Relapsing-Remitting MS: New Phase 2 Data

The second-generation selective DHODH inhibitor vidofludimus calcium met a phase 2 trial primary endpoint of suppressing new active lesions on MRI and was well tolerated. ....

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No Clear Answers From MS Drug Discontinuation Trial

The first randomized trial to examine if older adults with multiple sclerosis can discontinue disease-modifying therapy after years of being relapse-free failed to deliver a definitive conclusion. ....

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