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Health care artificial intelligence gets biased data creating unequal care

Heart Disease Genes Flagged by Rare Variant Analysis of Spontaneous Coronary Artery Dissection

With exome sequencing, researchers found risky rare variants in genes involved in vascular connective tissue disease, related monogenic conditions, or past association studies.

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

A study recently published in the top-tier journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) shows how a specific gene flow from Neandertals can act as a double-edged sword by increasing the risk for the development of severe coronavirus disease 2019 (COVID-19), and at the same time decreasing the risk for the infection with the human immunodeficiency virus (HIV).

Study increases knowledge of the genetics behind aortic aneurysm

Study increases knowledge of the genetics behind aortic aneurysm A new study increases knowledge of the genetics behind aortic aneurysm, a disease that can spark life-threatening events like aortic dissections and ruptures. University of Michigan Health-led researchers compared blood samples from more than 1,300 people who had a thoracic aortic aneurysm with more than 18,000 control samples, in partnership with U-M s Cardiovascular Health Improvement Project and its Michigan Genomics Initiative. Related Stories After examining nearly the entire human genome for genetic changes that increase risk of aneurysm, we discovered a new change in the genetic code of a transcription factor, which means it controls many other genes, explained co-corresponding author Cristen Willer, Ph.D., a professor of cardiovascular medicine, internal medicine, human genetics and computational medicine and bioinformatics at University of Michigan Health.

Unlocking genetic clues behind aortic aneurysm