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Study increases knowledge of the genetics behind aortic aneurysm
A new study increases knowledge of the genetics behind aortic aneurysm, a disease that can spark life-threatening events like aortic dissections and ruptures.
University of Michigan Health-led researchers compared blood samples from more than 1,300 people who had a thoracic aortic aneurysm with more than 18,000 control samples, in partnership with U-M s Cardiovascular Health Improvement Project and its Michigan Genomics Initiative.
Related Stories After examining nearly the entire human genome for genetic changes that increase risk of aneurysm, we discovered a new change in the genetic code of a transcription factor, which means it controls many other genes, explained co-corresponding author Cristen Willer, Ph.D., a professor of cardiovascular medicine, internal medicine, human genetics and computational medicine and bioinformatics at University of Michigan Health.
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