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Serial cross-sectional estimation of vaccine-and infection-induced SARS-CoV-2 seroprevalence in British Columbia, Canada

Background: The evolving proportion of the population considered immunologically naive versus primed for more efficient immune memory response to SARS-CoV-2 has implications for risk assessment. We sought to chronicle vaccine- and infection-induced seroprevalence across the first 7 waves of the COVID-19 pandemic in British Columbia, Canada.

Methods: During 8 cross-sectional serosurveys conducted between March 2020 and August 2022, we obtained anonymized residual sera from children and adults who attended an outpatient laboratory network in the Lower Mainland (Greater Vancouver and Fraser Valley). We used at least 3 immunoassays per serosurvey to detect SARS-CoV-2 spike and nucleocapsid antibodies. We assessed any seroprevalence (vaccineor infection-induced, or both), defined by positivity on any 2 assays, and infection-induced seroprevalence, also defined by dual-assay positivity but requiring both antinucleocapsid and antispike detection. We used estimates of infection-induced ....

United Kingdom , British Columbia , Suzana Sabaiduc , Michael Irvine , Romina Reyes , Samantha Kaweski , Mieke Fraser , Martin Petric , Shinhye Kim , Mel Krajden , Danuta Skowronski , Bonnie Henry , Paul Levett , Erica Chuang , Fraser Health Authority , Public Health Agency Of Canada Grant , World Health Organization , Bc Diagnostic Accreditation Program , Vancouver Coastal Health Authority , Canadian Institutes Of Health Research , British Columbia Centre For Disease Control , Public Health Agency Of Canada , Michael Smith Foundation For Health Research Grant , Lower Mainland , Greater Vancouver , Fraser Valley ,

Omicron variant: B.C.'s whole genome sequencing lab on the hunt for mutations

Every positive COVID-19 sample in B.C. is now being sent to the province’s whole genome sequencing lab in Vancouver, where they are being analyzed to determine if the patient was infected with the Omicron variant. ....

British Columbia , John Tyson , Natalie Prystajecky , Mel Krajden , Bc Centre For Disease , Disease Control ,

COVID-19: Unpredictable vaccine deliveries challenge B.C. program: Dix


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In the race between highly contagious COVID variants and B.C’s vaccination program, the province’s biggest hurdle has been the unpredictability of the vaccine supply from the federal government.
B.C. surpassed one million vaccine shots injected on Friday as it marked another grim daily COVID-19 case count with 1,262 new infections.
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COVID-19: Unpredictable vaccine deliveries challenge B.C. s vaccination program: Dix Back to video
There’s about a one-week turnaround between when vaccine shipments are received by the province and when they’re delivered to health authorities and vaccination clinics, Health Minister Adrian Dix said Thursday. In recent weeks, the province was left with less than a day’s supply of the Pfizer vaccine, Dix said, which meant health officials had to get new shipments out to clinics within one or two days to ensure people booked ....

British Columbia , Port Coquitlam , Patty Hajdu , Liz Baverstock , Katie Derosa , Mel Krajden , Doug Ford , Dany Fortin , Bonnie Henry , Adrian Dix , Brian Conway , Vancouver Infectious Diseases Centre , Bc Centre For Disease , Ministry Of Health , Vancouver Coastal Health , Richmond Teacher Association , Postmedia Network Inc , Alberta Health , Health Minister Adrian Dix , Health Minister Patty Hajdu , Postmedia News , Disease Control , Premier Doug Ford , Postmedia Network , Street East , பிரிட்டிஷ் கொலம்பியா ,