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Cureus | Bempedoic Acid's Use as an Adjunct in Lowering Low-Density Lipoprotein Cholesterol in Patients With Coronary Artery Disease: A Systematic Review

Coronary artery disease (CAD) is one of the leading causes of death worldwide. Atherosclerosis begins in childhood as fatty streaks, progresses with age, and lifestyle influences the progression of atherosclerotic plaque. Over time, with significant narrowing of the blood vessels, blood flow into the coronary arteries is compromised, resulting in various symptoms of coronary heart disease. Many drugs are used in clinical practice to prevent atherosclerotic cardiovascular events in patients with CAD. This review aims to investigate the efficacy and safety of a non-statin novel lipid-lowering drug, bempedoic acid (BDA), an adenosine triphosphate (ATP) citrate lyase inhibitor, in lowering serum low-density lipoprotein cholesterol (LDL-C) levels among patients with CAD. BDA is a new drug that recently got approval for clinical use. Following its discovery, BDA has been researched in order to investigate its role in the treatment of hypercholesterolemia. A search for studies was conducted u ....

United States , Raman Goit , American College Of Cardiology , Joanna Briggs Institute , Elton Bryson Stephens Company , Preferred Reporting Items , Systematic Reviews , Pubmed Central , Google Scholar , Coronary Artery Disease , Cardiovascular Disease , Critical Appraisal Checklist , Multiple Systematic Reviews , Narrative Review Articles , Randomized Controlled Trials , Medical Subject , World Journal , American College , Safety Outcome , Image Credit , Author Raman Goit , Non Statin Lipid Lowering ,

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Neue Öffnungszeiten beim Impfzentrum
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pnp.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pnp.de Daily Mail and Mail on Sunday newspapers.

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