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Masatoshi Nei, Kyoto Prize-winning evolutionary geneticist, dies at 92

Masatoshi Nei, Evan Pugh University Professor Emeritus at Penn State, a pioneering evolutionary geneticist and a laureate of the prestigious Kyoto Prize, has died at age 92. His extraordinary life was marked by transformative contributions to evolutionary genetics and biology. ....

United States , Beth Mcgraw , Masatoshi Nei , Marie Curie , Nikola Tesla , Tracy Langkilde , Thomas Edison , Sudhir Kumar , Nokuno Nei , Jonas Salk , Brown University , Evan Pugh University Professor Of Biology , Eberly College Of Science , Japan Society Of Animal Genetics , Population Genetics Laboratory , Kyoto Prize In Basic Sciences , University Of Texas At Houston , Japan Society Of Human Genetics , Japan Society For Histocompatibility , Institute Of Molecular Evolutionary Genetics , Society For Molecular Biology , Institute For Genomics , Evan Pugh University Professor Emeritus At Penn , Miyazaki University Of Japan , International Prize For Biology , National Institute Of Radiological Sciences ,

A unified global genotyping framework of dengue virus serotype-1 for a stratified coordinated surveillance strategy of dengue epidemics | Infectious Diseases of Poverty

Dengue is the fastest spreading arboviral disease, posing great challenges on global public health. A reproduceable and comparable global genotyping framework for contextualizing spatiotemporal epidemiological data of dengue virus (DENV) is essential for research studies and collaborative surveillance. Targeting DENV-1 spreading prominently in recent decades, by reconciling all qualified complete E gene sequences of 5003 DENV-1 strains with epidemiological information from 78 epidemic countries/areas ranging from 1944 to 2018, we established and characterized a unified global high-resolution genotyping framework using phylogenetics, population genetics, phylogeography, and phylodynamics. The defined framework was discriminated with three hierarchical layers of genotype, subgenotype and clade with respective mean pairwise distances 2–6%, 0.8–2%, and ≤ 0.8%. The global epidemic patterns of DENV-1 showed strong geographic constraints representing stratified spatial ....

United States , South Korea , Republic Of Korea , Koichiro Tamura , Monte Carlo , Sudhir Kumar , Masatoshi Nei , Pennsylvania State University , R Foundation For Statistical Computing , Virus Pathogen Resource , Hierarchical Bayesian Analysis , Population Structure , Tabless B , Bayesian Skyline , Markov Chain Monte Carlo , Trace Tracer , Statistical Computing ,

On the origin of this species - The Hindu BusinessLine

On the origin of this species
ISTOCK.COM - Getty Images×
A search is on for ‘patient zero’ the first ever case of Covid-19 as a team of genetic sleuths attempts to trace the mutation history of the deadly SARS-CoV2 virus
The novel coronavirus, which has caused untold miseries in almost every country in the world over the last one and a half years, is still shrouded in many mysteries. Even after nearly 15.7 crore cases and around 32.7 lakh deaths, scientists are still in the dark about the emergence of the very first case of human transmission.
Identifying the very first case what scientists call ‘patient zero’ is key to ascertaining how the virus SARS-CoV2 acquired the ability to infect humans. Besides, it can help draw up the evolutionary history of the virus, which has brought the world economy on its knees in a short span of time. ....

Temple University , United States , Sudhir Kumar , Masatoshi Nei , Birla Institute Of Technology , Institute For Genomics , Birla Institute , Founding Director , Evolutionary Medicine , Molecular Biology , கோயில் பல்கலைக்கழகம் , ஒன்றுபட்டது மாநிலங்களில் , ஸௌட்ஶ்ர் குமார் , பிர்லா நிறுவனம் ஆஃப் தொழில்நுட்பம் , நிறுவனம் க்கு மரபியல் , பிர்லா நிறுவனம் , ஸ்தாபகம் இயக்குனர் , பரிணாம வளர்ச்சி மருந்து , மூலக்கூறு உயிரியல் ,