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LSD, a future antianxiety pill? | McGill University Health Centre

A new study by Dr. Gabriella Gobbi reveals the neurobiological mechanisms by which LSD could relieve anxiety ....

Justinep Enns , Martha Lopez Canul , Athanasios Markopoulos , Antonio Inserra , Michael Pileggi , Gabriella Gobbi , Youssef El Rahimy , Professor Of Pharmacology At San Raffaele University , University Of Padua , Department Of Psychiatry At Mcgill University , Vita Salute San Raffaele University , Integrative Neuroscience Brain Program , Health Canada , Mcgill University , Mcgill University Health Centre , Pharmacological Sciences , Faculty Of Medicine Mcgill University , Brain Repair , Integrative Neuroscience , Research Institute , Neurobiological Psychiatry Unit , Danilo De Gregorio , Assistant Professor , San Raffaele University , Montreal General Hospital ,

LSD, future anti-anxiety pill?

LSD, future anti-anxiety pill?
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Justinep Enns , Martha Lopez Canul , Athanasios Markopoulos , Antonio Inserra , Michael Pileggi , Gabriella Gobbi , Youssef El Rahimy , Professor Of Pharmacology At San Raffaele University , University Of Padua , Department Of Psychiatry At Mcgill University , Vita Salute San Raffaele University , Integrative Neuroscience Brain Program , Health Canada , Mcgill University , Mcgill University Health Centre , Pharmacological Sciences , Faculty Of Medicine Mcgill University , Brain Repair , Integrative Neuroscience , Research Institute , Neurobiological Psychiatry Unit , Danilo De Gregorio , Assistant Professor , San Raffaele University , Montreal General Hospital ,

LSD, a future anti-anxiety pill?

A new study by Dr. Gabriella Gobbi reveals the neurobiological mechanisms by which LSD could relieve anxiety The craze for psychedelics used for therapeutic purposes is real. However, the scientific evidence supporting their effectiveness and explaining their mode of action in treating mental health disorders is still very thin. A new study led by Dr. Gabriella Gobbi, a senior scientist in the Brain Repair and Integrative Neuroscience (BRaIN) Program at the Research Institute of the McGill University Health Centre (RI-MUHC), sheds light on previously unexplained neurobiological mechanisms by which LSD is believed to relieve anxiety. While preliminary studies suggested that psychotherapy-assisted microdosing was effective in alleviating anxiety and depressive symptoms in people with severe psychiatric or neurological problems, the biological mechanisms underlying these effects had remained unclear to date. The study conducted by Dr. Gobbi's team demonstrates for the first time that ....

Martha Lopez Canul , Evelyne Dufresne , Justinep Enns , Antonio Inserra , Athanasios Markopoulos , Michael Pileggi , Gabriella Gobbi , Youssef El Rahimy , Professor Of Pharmacology At San Raffaele University , University Of Padua , Department Of Psychiatry At Mcgill University , Vita Salute San Raffaele University , Integrative Neuroscience Brain Program , Health Canada , Mcgill University , Mcgill University Health Centre , Pharmacological Sciences , Faculty Of Medicine Mcgill University , Brain Repair , Integrative Neuroscience , Research Institute , Neurobiological Psychiatry Unit , Danilo De Gregorio , Assistant Professor , San Raffaele University , Montreal General Hospital ,

New use for an old drug: How does ketamine combat depression?

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A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.
Because more than 30% of patients are resistant to selective serotonin reuptake inhibitors (SSRI), the most commonly-prescribed antidepressants, finding an effective treatment for major depressive disorder is challenging.
Initially, ketamine was approved for anesthesia and pain relief. Since its discovery, researchers have been studying new uses for this drug, and ketamine was approved last year for patients with major depression who are treatment-resistant. Unlike standard antidepressants, which can take several weeks to have an effect, ketamine works within hours. Until now, little was known about the molecular mechanism that triggers the antidepressant ....

Martha Lopez Canul , Natalina Salmaso , Angelica Torres Berrio , Stephanie Simard , Garethm Rurak , Agnieszka Skaleka , Sara Bermudez , Edna Matta Camacho , Nahum Sonenberg , Mohammadj Eslamizade , Abdessattar Khlaifia , Gabriella Gobbi , Jean Claude Lacaille , Department Of Biochemistry At Mcgill University , Mcgill University , Department Of Psychiatry At Mcgill University , Department Of Neurosciences At Universit , Carleton University , Argel Aguilar Valles , Danilo De Gregorio , ஏஞ்சலிகா டோரஸ் பெரியோ , மாற்றாந்தாய் சிமார்ட் , சாரா பெர்முடெஸ் , எட்னா மட்டா காமக்கோ , துறை ஆஃப் உயிர் வேதியியல் இல் மகில் பல்கலைக்கழகம் , மகில் பல்கலைக்கழகம் ,