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Nixing bone cancer fuel supply offers new treatment approach, mouse study suggests | The Source

Two drugs targeting cancer cells’ energy source potentially could replace toxic chemo in osteosarcoma
January 26, 2021
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A new study from Washington University School of Medicine in St. Louis suggests that a two-drug combination targeting a tumor’s energy sources could be as effective and less toxic than methotrexate, a long-used chemotherapy drug often given in high doses to treat osteosarcoma, a bone cancer. Shown is a cross section of osteosarcoma. (Image: Richa Rathore)
An innovative approach to treating bone tumors starving cancer cells of the energy they need to grow could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis. Studying human cancer cells and mice, the researchers said that a two-drug combination targeting a tumor’s energy sources could be as effective and less toxic than methotrexate, a l ....

United States , Luminex Flexmap , Laura Shelton , Richa Rathore , School Of Medicine , Sarcoma Foundation Of America , Siteman Cancer Center At Barnes , National Cancer Institute , National Institutes Of Health , Washington University School Of Medicine , Siteman Cancer Center , Kellsie Hope Foundation , Washington University Diabetes Research Center , Immunomonitoring Laboratory , Washington University Surgical Oncology Training Grant , Cancer Center Support Grant , Washington University School , Brian Van Tine , Van Tine , Young Adult , Barnes Jewish Hospital , Siteman Kids , Louis Children , Dawn Merkel , Bone Chili Cook Off , Hope Foundation ,

Nixing bone cancer fuel supply offers new treatment approach, mouse study suggests

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IMAGE: A new study from Washington University School of Medicine in St. Louis suggests that a two-drug combination targeting a tumor s energy sources could be as effective and less toxic than.
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Credit: RICHA RATHORE
An innovative approach to treating bone tumors - starving cancer cells of the energy they need to grow - could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis. Studying human cancer cells and mice, the researchers said that a two-drug combination targeting a tumor s energy sources could be as effective and less toxic than methotrexate, a long-used chemotherapy drug often given in high doses to treat osteosarcoma, a bone cancer. ....

United States , Luminex Flexmap , Laura Shelton , Richa Rathore , School Of Medicine , Sarcoma Foundation Of America , Siteman Cancer Center At Barnes , National Cancer Institute , National Institutes Of Health , Washington University School Of Medicine , Siteman Cancer Center , Kellsie Hope Foundation , Washington University Diabetes Research Center , Immunomonitoring Laboratory , Washington University Surgical Oncology Training Grant , Cancer Center Support Grant , Washington University School , Brian Van Tine , Van Tine , Young Adult Sarcoma , Barnes Jewish Hospital , Siteman Kids , Louis Children , Dawn Merkel , Bone Chili Cook Off , Hope Foundation ,