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Researchers identify an unexpected driver of cancer immunotherapy resistance

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signaling on tumor-killing CD8+ T cells. ....

Hong Kong , Che Chi Ming , Huang Yuanhua , Stephanie Ma Kwai Yee , Emily Henderson , Javed Asif , Guang Sheng , Lok Chun Nam , Teo Jia Ming Nickolas , Chen Weixin , Technology Parks Corporation , Department Of Chemistry , University Of Hong Kong Hkumed , School Of Biomedical Sciences , Key Laboratory Of Synthetic Chemistry , Typei Interferon , Industry Focus , Heidi Ling Guang Sheng , Assistant Professor , Biomedical Sciences , Yau Siu Wah , Hong Kong Science , Technology Parks , Professor Che Chi Ming , State Key Laboratory , Synthetic Chemistry ,

HKUMed Finds Unexpected T Cell Exhaustion Factor in Cancer Immunotherapy Resistance

HKUMed Finds Unexpected T Cell Exhaustion Factor in Cancer Immunotherapy Resistance
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Hong Kong , Che Chi Ming , Huang Yuanhua , Stephanie Ma Kwai Yee , Javed Asif , Victor Gray , Guang Sheng , Lok Chun Nam , Teo Jia Ming Nickolas , Chen Weixin , Technology Parks Corporation , Department Of Chemistry , Research Fellow Scheme , University Of Hong Kong Hkumed , School Of Biomedical Sciences , Key Laboratory Of Synthetic Chemistry , Research Fund , Heidi Ling Guang Sheng , Typei Interferon , Cell Reports , Assistant Professor , Biomedical Sciences , Yau Siu Wah , Hong Kong Science , Technology Parks , Professor Che Chi Ming ,