A natural killer cell
NIAID
Scientists have started to test whether natural killer, or NK, cells can be trained to go after hard-to-cure blood cancers in human patients. But making these sentinels of the innate immune system a potential boon to human health spans might be simpler: Rather than needing to be genetically engineered or primed with synthetic antibodies, they just need to be turned on.
In mice, researchers reported on Monday in the journal Med, activating NKT cells can eliminate the senescent cells partly responsible for many diseases of aging. If the results hold up, they could offer a promising alternative to “senolytics” experimental drugs that destroy these zombified cells that pile up and pollute your tissues as you get older. Although dozens of such drugs have postponed or even reversed diseases of aging in mouse experiments, clinical trials have thus far underwhelmed.
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I m Ed, and I m an engineer on the DevEx team here - you might have seen me around HN here and there. ;) This is, and I have to stress that I m not kidding because everybody says this sort of thing, for real my favorite job that I ve ever had. The team here is mind-blowingly smart, there is a real and concerted focus on not just competence but on the human side of things; one of the company s core values is be human and I thought it was marketing stuff til I joined and learned to my surprise that it is emphatically not. Also? Legit, the best onboarding experience I ve ever had. During a pandemic, no less.
Teleport (YC S15) | Backend Engineer | US, Europe, Canada, Remote OK | https://goteleport.com
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Luke Storey commits his first hack at dawn precisely when the sun crests the horizon at a 30-degree angle, providing a supercharged light that he swears optimally dials his circadian rhythm and neurotransmitters. Sungazing is often followed by a ten-minute plunge in an industrial freezer full of 40-degree water a jerry-rigged ice bath. After toweling off, the rangy, six-foot-three 50-year-old then ascends to the top of his Laurel Canyon property where he has converted a toolshed into a new-age gym that looks like it was outfitted by someone who has watched the
Iron Man trilogy a few too many times. There’s a hyperbaric chamber that he meditates in before he flips on the mitochondria-boosting light panels that hang from the walls. Naked, he stands for five minutes on a full-body-vibration plate before he plops into a chair covered by an infrared heating pad and plugs himself into several gizmos as he absorbs the natural energies emitted from a $15,000 machine called the Biocharger