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Beyond chemotherapy: Navigating the promise and perils of CAR-T therapy in pediatric cancer

Upon hearing the phrase ‘cancer treatment’, the first word that can typically spring to mind is chemotherapy – a primary therapy which uses powerful chemicals to destroy rapidly growing cancer cells in the body.

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Brian-koffman
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Lucy-ellerker

Tisagenlecleucel Yields Durable Responses in R/R Follicular Lymphoma

Patients with relapsed/refractory follicular lymphoma experienced durable responses when treated with tisagenlecleucel (Kymriah) in the phase 2 ELARA study (NCT03568461), according to data presented at the 2023 ASH Annual Meeting.

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Elara-study
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Researchers Highlight Restrictive Coverage of Gene, Cell Therapies

The researchers focused on coverage trends across an array of disease states, including lymphoma, vision loss, and spinal muscular atrophy, finding discrepancies in coverage across 16 states and Medicaid Care Organizations.

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Centers-of-excellence

As Cell Therapy Gains Ground, Efforts Emerge to Improve CAR T-Manufacturing

Cell therapy offers a treatment option for some advanced blood cancers, but the manufacturing process is lengthy and complex. The biopharmaceutical industry is working on various technologies that could make manufacturing faster and more efficient, or perhaps supplant the current process altogether.

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Novartis Pharma AG: Novartis five-year Kymriah data show durable remission and long-term survival maintained in children and young adults with advanced B-cell ALL

In final ELIANA analysis, 55% of patients with relapsed or refractory (r/r) B-cell acute lymphoblastic leukemia (ALL) who were treated with CAR-T cell therapy Kymriah were still alive after five years1 Nearly

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