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Kimberly G. Blumenthal, M.D., MSc
Most patients with immediate and potentially allergic reactions to COVID-19 vaccines from Pfizer-BioNTech and Moderna can safely tolerate a second dose, according to a multisite study.
Investigators analyzed data from patients who sought specialist hospital care after reacting to their first mRNA COVID-19 vaccine dose. “These reactions could include symptoms such as itching or hives or flushing,” reported study co-author Matthew S. Krantz, M.D., of Vanderbilt University Medical Center.
Fully 17% of the 189 study participants experienced anaphylaxis â an acute reaction â after the first dose. Among the 159 who received a second dose, 20% had reactions that were mild or resolved by antihistamines. But all of these individuals â including 19 who had initially experienced anaphylaxis â safely completed vaccination. Whatâs more, all were cleared to receive an mRNA vaccine shot in the future w
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