food plant and the storm in the midwest, new evacuation and the major concerns tonight top republicans i in the house meeting former president trump and pelosi s warning that the enemy is within the house. nbc news exclusive president biden reunited families separated at the border why is his task force delayed? what does it mean for your store credit cards this is nbc news with lester holt good evening, the way to vaccine our way out of the pandemic got more complicated with the discovery of the south african strain in the united states. two strangers did not travel anywhere testing positive for the virus. we are trying to understand if they are more threatening or how effective vaccines are against them the demand for vaccinations still far exceeding supplies in the country tonight. we ll take you to the state getting attention for a vaccine roll out that appears to be working. how they cracked the code. first, let s get the latest on the variant. here is miguel almague