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Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows
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Chikako Nakajima , Masato Sawada , Kazunobu Sawamoto , Professor At Nagoya City University , National Institute For Physiological Sciences , Nature Communications , Nagoya City University Gradualte School , Medical Sciences , Nagoya City University , National Institute , Physiological Sciences ,

Deciphering the tip of migrating neurons: Dis

<p>The structure and functions of the tip of migrating neurons remain elusive. Here, a research group led by Kazunobu Sawamoto, Professor at Nagoya City University and National Institute for Physiological Sciences, and by Chikako Nakajima and Masato Sawada, staff scientists in his laboratory, has elucidated that the PTP&sigma;-expressing growth cone senses the extracellular matrix and drives neuronal migration in the injured brain, leading to functional recovery.</p>
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Chikako Nakajima , Masato Sawada , Kazunobu Sawamoto , Method Of Research , Nagoya City University , University Of Valencia , Nikke Medical Co Ltd , Doshisha University , York University , Jichi Medical University , Friedrich Schiller University Jena , Toray Research Center Inc , Nature Communications , Japan Wool Textile Co Ltd , National Institute For Physiological Sciences , Niigata University , University Of Pennsylvania , Kyoto University , Professor At Nagoya City University , National Institute , Physiological Sciences , Toray Research Center , New York University ,

Synaptic Pruning and New Neuron Maturation in the Adult Brain

In the mammalian brain, neural stem cells exist even after birth, and new neurons are produced. As these new neurons mature, they form synapses with existing neurons to create functional neural circuits. For the brain to develop and function normally, it is important to maintain an appropriate number of synapses, but the mechanism to regulate the number of synapses has not been fully understood. ....

Kazunobu Sawamoto , Chihiro Kurematsu , Nagoya City University School Of Medicine , Institute Of Brain Science , Brain Science , Nagoya City University Graduate School , Medical Sciences , Nagoya City University School ,