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Nanotechnology Now - Press Release: University of Toronto researchers discover new lipid nanoparticle that shows muscle-specific mRNA delivery, reduces off-target effects: Study findings make significant contribution to generating tissue-specific ionizable lipids and prompts rethinking of mRNA vaccine design princi

University of Toronto researchers discover ne

<p>A team of researchers based at the <a href="https://www.pharmacy.utoronto.ca/">University of Toronto&rsquo;s (U of T) Leslie Dan Faculty of Pharmacy</a> has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues. The team also showed that mRNA delivered by the lipid nanoparticles investigated in their study triggered potent cellular-level immune responses as a proof-of-concept melanoma cancer vaccine.</p>

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