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GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

A new research paper was published in Oncotarget's Volume 14 on December 20, 2023, entitled, "The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies." ....

Qiang Lu , Lili Tang , Fubo Xie , Siyuan Le , Fusheng Zhou , Jinmin Ren , Dragan Cicic , Genfleet Therapeutics Inc , Sellas Life Sciences Group , Jiong Lan , Genfleet Therapeutics , Cell Cycle , N Vivo , Protein Expression ,

GFH009: Potent, Selective CDK9 Inhibitor for Hematologic Cancer

GFH009: Potent, Selective CDK9 Inhibitor for Hematologic Cancer
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Jinmin Ren , Dragan Cicic , Lili Tang , Fubo Xie , Fusheng Zhou , Qiang Lu , Siyuan Le , Sellas Life Sciences Group , Genfleet Therapeutics Inc , Oncotarget Volume , Jiong Lan , Genfleet Therapeutics ,