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Alkermes Announces Clinical Trial Collaboration and Supply Agreement With MSD to Evaluate Nemvaleukin Alfa in Combination With KEYTRUDA in Patients With Platinum-Resistant Ovarian Cancer


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DUBLIN, April 7, 2021 /PRNewswire/ Alkermes plc (Nasdaq: ALKS) today announced that it has entered into a clinical trial collaboration and supply agreement with MSD (a tradename of Merck & Co., Inc. Kenilworth, NJ, USA) for a planned phase 3 study to evaluate nemvaleukin alfa ( nemvaleukin , formerly referred to as ALKS 4230), Alkermes novel investigational engineered interleukin-2 (IL-2) variant immunotherapy, in combination with MSD s KEYTRUDA
(pembrolizumab), in comparison to investigator choice chemotherapy in patients with platinum-resistant ovarian cancer. Under the terms of the agreement, Alkermes is responsible for conducting the phase 3 study, which is planned to initiate in the second half of 2021.
We are pleased to collaborate with MSD to evaluate nemvaleukin in combination with KEYTRUDA in patients with platinum-resistant ovarian cancer, a patient population for which there are limited treatment options available and overall survival remains low. I ....

United States , Sandy Coombs , Jessicca Rege , Sourojit Bhowmick , Merck Co Inc , Exchange Commission , Clinical Development Program , Merck Sharp Dohme Corp , Vice President , Private Securities Litigation Reform Act , Annual Report , Merck Sharp , Dohme Corp , ஒன்றுபட்டது மாநிலங்களில் , மணல் கும்பஸ் , மெர்க் இணை இன்க் , பரிமாற்றம் தரகு , மருத்துவ வளர்ச்சி ப்ரோக்ர்யாம் , துணை ப்ரெஸிடெஂட் , ப்ரைவேட் பத்திரங்கள் வழக்கு சீர்திருத்தம் நாடகம் , ஆண்டு அறிக்கை , மெர்க் கூர்மையான ,

Alkermes In Clinical Trial Collaboration With Merck


Alkermes In Clinical Trial Collaboration With Merck
WASHINGTON (dpa-AFX) - Alkermes plc (ALKS) has entered into a clinical trial collaboration and supply agreement with Merck & Co. for a planned phase III study of Alkermes nemvaleukin alfa in combination with Merck s Keytruda in patients with platinum-resistant ovarian cancer, Alkermes said in a release.
As per the agreement, Alkermes plans to initiate the phase III study in the second half of 2021.
We are pleased to collaborate with MSD to evaluate nemvaleukin in combination with KEYTRUDA in patients with platinum-resistant ovarian cancer, a patient population for which there are limited treatment options available and overall survival remains low. Importantly, there are no anti-PD-1 treatments currently approved for this tumor type, said Jessicca Rege, Ph.D., Vice President, Head of Oncology at Alkermes. ....

United States , Merck Keytruda , Jessicca Rege , Merck Co , Vice President , ஒன்றுபட்டது மாநிலங்களில் , மெர்க் இணை , துணை ப்ரெஸிடெஂட் ,

Alkermes Announces Clinical Trial Collaboration and Supply Agreement With MSD to Evaluate Nemvaleukin Alfa in Combination With KEYTRUDA® in Patients With Platinum-Resistant Ovarian Cancer


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DUBLIN, April 7, 2021 /PRNewswire/  Alkermes plc (Nasdaq: ALKS) today announced that it has entered into a clinical trial collaboration and supply agreement with MSD (a tradename of Merck & Co., Inc. Kenilworth, NJ, USA) for a planned phase 3 study to evaluate nemvaleukin alfa ( nemvaleukin , formerly referred to as ALKS 4230), Alkermes novel investigational engineered interleukin-2 (IL-2) variant immunotherapy, in combination with MSD s KEYTRUDA
® (pembrolizumab), in comparison to investigator choice chemotherapy in patients with platinum-resistant ovarian cancer. Under the terms of the agreement, Alkermes is responsible for conducting the phase 3 study, which is planned to initiate in the second half of 2021. ....

United States , Sandy Coombs , Jessicca Rege , Sourojit Bhowmick , Merck Co Inc , Exchange Commission , Clinical Development Program , Merck Sharp Dohme Corp , Vice President , Private Securities Litigation Reform Act , Annual Report , Merck Sharp , Dohme Corp , ஒன்றுபட்டது மாநிலங்களில் , மணல் கும்பஸ் , மெர்க் இணை இன்க் , பரிமாற்றம் தரகு , மருத்துவ வளர்ச்சி ப்ரோக்ர்யாம் , துணை ப்ரெஸிடெஂட் , ப்ரைவேட் பத்திரங்கள் வழக்கு சீர்திருத்தம் நாடகம் , ஆண்டு அறிக்கை , மெர்க் கூர்மையான ,