Hi. Wow. How are you doing . Wow. What a great crowd. Welcome to hannity and god i bless america. Ill say this. I start with bad news. Sjoe. Still your president , kamala, still your vickamalae president t back with our studio audience. These are the only people in the citk righ y and of new york right here in this room. Thank you for coming. Thank you for being at hom jusah and in just a moment, by the way, the man that could be Theeo Nextusm speaker of the house, jim jordan, will join us live from capitol hill. Now, just prior to coming on the air, i have gotten confirmation that President Donald Trump will be announcing his endorsement of jim jordan for speaker. Sero thats news that we have as we start the show tonight. Ky we will also tonight be hearing from former kentucky, kentuckys senator rand paul. Tomi lahren is here with us. Jimmy fallon and in studio with us. But first, i want to start a word about what the media mob is calling a monument to white supremacy. Remember that .
Testicular germ cell tumours (TGCTs) are the most common malignancy in young men. Originating from foetal testicular germ cells that fail to differentiate correctly, TGCTs appear after puberty as germ cell neoplasia in situ cells that transform through unknown mechanisms into distinct seminoma and non-seminoma tumour types. A balance between activin and BMP signalling may influence TGCT emergence and progression, and we investigated this using human cell line models of seminoma (TCam-2) and non-seminoma (NT2/D1). Activin A- and BMP4-regulated transcripts measured at 6 h post-treatment by RNA-sequencing revealed fewer altered transcripts in TCam-2 cells but a greater responsiveness to activin A, while BMP4 altered more transcripts in NT2/D1 cells. Activin significantly elevated transcripts linked to pluripotency, cancer, TGF-β, Notch, p53, and Hippo signalling in both lines, whereas BMP4 altered TGF-β, pluripotency, Hippo and Wnt signalling components. Dose-dependent antagonism of BMP