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COVID-19 vaccination induces highly variable immunity among the immunocompromised

COVID-19 vaccination induces highly variable immunity among the immunocompromised Researchers in the United States have conducted a study showing that the humoral (antibody) immunity induced by vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – varies significantly among immunocompromised individuals. The findings come from an interim analysis of an ongoing observational, prospective cohort analysis called the COVID-19 Vaccination in the Immunocompromised Study (CoVICS), which began on April 14 th, 2021. Ghady Haidar and colleagues report that the presence of antibodies (seropositivity) against SARS-CoV-2 was significantly lower among certain groups of immunocompromised individuals compared with among healthy vaccinees.

Study: Immunocompromised Response to COVID-19 Vaccination