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Low-sodium Oxybate Improves Idiopathic Hypersomnia Symptoms, Even Sleep Inertia

Low-sodium oxybate treatment may improve sleep inertia via changes in VAS-SI scores, for patients with idiopathic hypersomnia.

United statesAmerican academy of neurologyIdiopathic hypersomnia severity scaleEpworth sleepiness scalePatient global impression

Zevra Highlights Plans to Advance IH, Narcolepsy Drug Candidate

Zevra reported progress in 2023, including results from a phase 2 study for idiopathic hypersomnia and plans to expand into narcolepsy.

Neilf mcfarlaneDrug administrationZevra therapeutics incInvestigational new drugTherapeutics incEpworth sleepinessIdiopathic hypersomnia severity scaleSleep inertia visual analog scaleBrain fog

KP1077 Is Safe, Tolerable for Improving Idiopathic Hypersomnia Symptoms

A phase 2 trial found KP1077 provides clinically meaningful benefits for idiopathic hypersomnia.

United statesChristopher drakeHenry ford health christopher drakeAmerican academy of sleep medicineDrug administrationUs drug enforcement agencyHenry ford healthZevra therapeuticsAmerican academyOrphan drug designationEnforcement agencyEpworth sleepiness scaleIdiopathic hypersomnia severity scaleSleep inertia visual analog scaleEpworth sleepinessBrain fog severity scale

Zevra Reports Positive Phase 2 Results for IH Drug Candidate

Zevra Therapeutics announced positive topline results from its phase 2 clinical trial evaluating KP1077 for idiopathic hypersomnia (IH).

Putilich dreamstimeChristopher drakeNeil mcfarlaneDrug administrationZevra therapeuticsEpworth sleepiness scaleIdiopathic hypersomnia severity scaleSleep inertia visual analog scaleBrain fog

Zevra Therapeutics Announces Top-Line Data from the Phase 2

KP1077 demonstrates clinically meaningful benefits for key IH symptoms Top-line data provide key information for the design of a Phase 3 study .

United statesChristopher drakeNeil mcfarlaneNichol ochsnerIgnacio guerrero rosAdannag alexanderZevra therapeutics incUs drug enforcement agencyDrug administrationExchange commissionEpworth sleepiness scaleIdiopathic hypersomnia severity scaleSleep inertia visual analog scalePrincipal investigatorChief executive officerBrain fog

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