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Adjusting Starting Points for Initial Price Offers: The Example of Ibrutinib

Ibrutinib has been selected for Medicare price negotiation under the Inflation Reduction Act. The authors summarize the House Oversight Committee investigation to be considered by CMS during the price negotiation process. ....

United States , Eli Lilly , Jasonb Gibbons , Charlesl Bennett , Committee On Oversight , Department Of Health , University Of South Carolina College Pharmacy , University Of Colorado Anschutz Medical Campus , Department Of Internal Medicine , Health Affairs Forefront , Northwestern University Feinberg School Of Medicine , Division Of Hematology Oncology , Us House Committee On Oversight , Us House Of Representatives Committee On Oversight , A View From Congress , National Cancer Institute , House Oversight Committee , Department Of Health Systems , Inflation Reduction Act , Representatives Committee , Orphan Drug , House Oversight , Health Policy , Johns Hopkins University Bloomberg School , Public Health , Health Systems ,

Observational Study Shows Frontline Ibrutinib With/Without Rituximab Is Safe and Effective in Low-Risk Mantle Cell Lymphoma

Ibrutinib with or without rituximab was effective and tolerable in patients with previously untreated, low-risk mantle cell lymphoma. ....

United Kingdom , Ibrutinib Imbruvica , Ann Tivey , International Prognostic Score Index , University Of Manchester , Prognostic Score Index , Mantle Cell Lymphoma ,

Primary Analysis of the SYMPATICO trial in Mantle Cell Lymphoma

Focusing on mantle cell lymphoma, Lori A. Leslie, MD, reviews the primary analysis of the SYMPATICO trial investigating ibrutinib-venetoclax combination therapy. ....

Lori Leslie , Jamesk Mccloskey , Gloria Leslie , Hackensack University Medical Center , John Theurer Cancer Center , Research Programs , Peer Exchange , Hackensack University Medical , Associate Professor , Indolent Lymphoma , While Bruton , Mash 2023 , Sympatico Study , Sympatico Trial , Mantle Cell Lymphoma , Btk Inhibitors , Combination Therapy ,

Discontinuation of Ibrutinib Is Common in Older Patients With CLL, Study Finds

Patients with chronic lymphocytic leukemia (CLL) who discontinued ibrutinib had higher rates of adverse events compared with those who continued the therapy, the authors found. ....

Pharmacyclics Janssen , Image Credit , Cancer Medicine , Chronic Lymphocytic Leukemia ,

Emerging Agents in GVHD: Axatilimab

The panel reviews axatilimab, an emerging agent for chronic GVHD under clinical studies. The experts explore findings from the Agave-201 study, highlighting potential challenges of intravenous administration and axatilimab’s unique mechanisms. ....

Dana Farber Cancer Institute , United States , Corey Cutler , Hannah Choe , Mitchell Horwitz , Bin Chen , Ohio State University , Marrow Transplant Program At Duke University , Professor Of Medicine At Harvard Medical School , Cell Therapy Program At Massachusetts , Cell Therapy Program , Massachusetts General Hospital , Harvard Medical School , Stem Cell Transplant Program , Adult Blood , Marrow Transplant Program , Duke University , Assistant Professor , Ohio State , Chronic Graft Versus Host Disease , Csf 1r Inhibitor , Iv Infusion , Agave 201 , Ast Alt Levels , Combination Therapy , Dash Conference ,