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Highly targeted CRISPR delivery system advanc

<p>By attaching two kinds of antibody fragments to membrane-derived globules, UC Berkeley researchers selectively delivered CRISPR-Cas9, guide RNA and a transgene to T-cells in living mice to create CAR T-cells. While this technique could make it easier to create CAR T-cells <em>in vivo</em> for cancer therapy, the ultimate goal is to selectively target CRISPR-filled &quot;enveloped delivery vehicles&quot; to any type of cell and avoid the <em>ex vivo</em> cell editing now used in current gene therapies.</p>

Researchers use ancient DNA to map migration during the Roman Empire

When and how immune cells decide to form path

<p>Unexpected findings have emerged about how and when certain infection-killing white blood cells decide to form memories about their encounters with a pathogen.&nbsp;</p> <p>These cells can turn themselves into durable memory cells that can survive a long time after an&nbsp;initial infection is cleared. They are&nbsp;prepared to&nbsp;recognize and eliminate future intrusions by the same kind of pathogen.</p> <p>That is one reason people are resistant to some infectious diseases after exposure to or recovery from the illness. Vaccinations also work this way, by teaching the immune system to spot and attack dangerous viruses, parasites or bacteria.</p> <p>Researchers have discovered a reversible switch in cytotoxic T lymphocytes, a type of immune white blood cell that directly destroys infected cells. The switch enables cells that have decided to become short-lived effector cells with potent cell-killing ability to reverse co

CCDD ID Epi Seminar Series

Justice, one class at a time: The biology department's fight to revolutionize assessments in STEM