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Hospitalized COVID-19 Patients Develop at Least One Symptom After 6 Months by Hannah Joy on January 11, 2021 at 7:08 PM The Lancet. The cohort study, looking at long-term effects of COVID-19 infection on people hospitalized in Wuhan, China, reveals that the most common symptom to persist is fatigue or muscle weakness (63% of patients), with patients also frequently experiencing sleep difficulties (26%). Anxiety or depression was reported among 23% of patients. Patients who were severely ill in hospital more often had impaired lung function and abnormalities detected in chest imaging - which could indicate organ damage - six months after symptom onset. ‘More than three quarters of COVID-19 patients have at least one ongoing symptom six months after initially becoming unwell. ....