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Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people
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Bioscience Nagahama , Fluidigm Snptype , Japan Public Health Prospective , Epidemiologic Research Program At Aichi Cancer Center , Tohoku Medical Megabank Community , Hospital Based Epidemiologic Research Program , Aichi Cancer Center , Japan Multi Institutional Collaborative Cohort , Japan Public Health Center Based Prospective , Tohoku Medical Megabank Community Based Cohort , Nagahama Prospective Cohort , Comprehensive Human Bioscience , Biobank Japan , Supplementary Materials , Project Phase , East Asian , Genotype Tissue Expression , East Asians , Aichi Cancer ,

H Pylori, Pathogenic Variants Interact to Increase Risk of Gastric Cancer

H pylori infection may further increase the risk of gastric cancer associated with germline pathogenic variants in cancer-predisposing genes. ....

Epidemiologic Research Program At Aichi Cancer Center , Healthday News , New England Journal , Hospital Based Epidemiologic Research Program , Aichi Cancer ,

A 'Double Whammy' for Gastric Cancer Risk

<em>H. pylori</em> infection and certain pathogenic variants linked with large excess risk ....

United States , Mike Bassett , Yukihide Momozawa , Epidemiologic Research Program At Aichi Cancer Center , Integrative Medical Sciences , University Of Zurich , New England Journal , Double Whammy , Gastric Cancer Risk , Biobank Japan , Hospital Based Epidemiologic Research Program , Aichi Cancer Center , England Journal , Englj Med ,

Genetic variants increase risk for H. pylori -related stomach cancer

Individuals with certain germline pathogenic variants had a substantially higher risk for developing gastric cancer after Helicobacter pylori infection, results of a Japan-based case-control study showed.The findings, published in The New England Journal of Medicine, suggest risk for gastric cancer is more heavily related to hereditary factors than previously thought, the investigators noted. ....

Yoshiaki Usui , Yukihide Momozawa , Laboratory For Genotyping Development , Epidemiologic Research Program At Aichi Cancer Center , Integrative Medical Sciences , Thenew England Journal , East Asian , Genotyping Development , Biobank Japan , Hospital Based Epidemiologic Research Program , Aichi Cancer Center , Molecular Cancer Research ,