Parkinson’s UK is investing £2.1million to support Neumora Therapeutics to carry out preclinical testing of NMRA-NLRP3, a NLRP3 inhibitor with the potential to reduce inflammation and protect brain cells in Parkinson’s. NLRP3 is a protein that plays a role in regulating a number of inflammatory processes that are believed to contribute to the damage to brain cells that underlies Parkinson’s.
A new study by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests a common brain network exists between heart rate deceleration and depression.
This article explores the role of citrullination, a post-translational modification process, in the pathogenesis of chronic diseases such as rheumatoid arthritis, cancer, and neurodegenerative disorders