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Low dose of AstraZeneca may be key to success
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January 16, 2021 12.04am
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Your writer mentions the mystery of the 90 per cent efficacy rate for those people who accidently received a low dose in the AstraZeneca trial, followed by a standard dose ( Gambling on the right vaccine , January 15). No matter why it happens, why not adopt this as standard immunisation practice rather than implement a procedure with only 65 per cent efficacy?
Diana Wyndham, North Sydney
Reluctance to adopt the AstraZeneca vaccine compared with Pfizer vaccine centres around the efficacy disparity - 65 per cent versus 90 per cent in the latter ( Comparing virus shots is tricky, especially at speed , January 15). Although not yet fully understood, a half dose of the AstraZeneca given first by mistake followed by a full dose produced 90 per cent efficacy in phase three of the trial. Why woul