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Base editing shows potential superiority for

Adenosine base editing restarted fetal hemoglobin expression in cells from patients with sickle cell disease. Find how St. Jude & Broad are advancing to a cure. ....

United States , Yong Cheng , Yoonjeong Jang , Jingjing Chen , Yu Yao , Rachel Levine , Senthil Velan Bhoopalan , Ruopeng Feng , Mitchell Weiss , David Liu , John Tisdale , Yichao Li , Shondra Pruett Miller , Akshay Sharma , Henry Bell , Thiyagaraj Mayuranathan , Gregory Newby , Richard Merkin , Shengdar Tsai , Shaina Porter , Erin Dempsey , Nikitha Nimmagadda , Kalin Mayberry , Merlin Crossley , Guolian Kang , Cicera Lazzarotto ,

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia. ....

United States , Lily Ramsey , Senthil Velan Bhoopalan , Cicera Lazzarotto , Guolian Kang , Yong Cheng , Phillip Doerfler , Erin Dempsey , Mitchell Weiss , Gregory Newby , Ruopeng Feng , Yu Yao , Rachel Levine , Jingjing Zhang , Shengdar Tsai , Henry Bell , Yoonjeong Jang , Jingjing Chen , Richard Merkin , Kalin Mayberry , Merlin Crossley , David Liu , Thiyagaraj Mayuranathan , John Tisdale , Yichao Li , Shaina Porter ,