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The NICE-SUGAR trial: Intensive glycemic control harmful in the ICU [Classics Series]

Intensive glucose control to target 81-108 mg/dL significantly increased 90-day mortality compared to conventional glucose control to target ≤180 mg/dL. ....

New Zealand , Glycemic Control , Nice Sugar Trial , Mergent And Pulmonary Care Classics , General Medicine Classics , The Classics ,

The Lee index: Risk of perioperative cardiac events [Classics Series]

1. The Lee index is a prospectively validated model that predicts the risk of a cardiac event in patients undergoing noncardiac surgery. 2. The six independent predictors are as follows: 1) high-risk surgery, 2) history of ischemic heart disease, 3) history of congestive heart failure, 4) history of cerebrovascular disease, 5) preoperative treatment with insulin, ....

American College Of Cardiology Heart Association , American College , American Heart Association , Revised Cardiac Risk Index , Lee Index , General Medicine Classics , Surgery Classics , The Classics ,

The ORACLE trial: Antibiotics for preterm, prelabor rupture of membranes [Classics Series]

1. Among infants born to women with preterm, premature rupture of membranes, those whose mothers were randomized to treatment with erythromycin experienced a lower incidence of adverse neonatal outcomes and prolongation of pregnancy compared to the placebo group. Original Date of Publication: March 2001 Study Rundown: Preterm, premature (prelabor) rupture of membranes (PPROM) is a ....

United Kingdom , Preterm Premature Rupture Of Membranes Pprom , General Medicine Classics , Obstetrics And Gynecology Classics , The Classics ,

The Child-Pugh score: Prognosis in chronic liver disease and cirrhosis [Classics Series]

1. The Child-Pugh score consists of five clinical features and is used to assess the prognosis of chronic liver disease and cirrhosis. 2. The Child-Pugh score was originally developed in 1973 to predict surgical outcomes in patients presenting with bleeding esophageal varices. 3. The score is used with the Model for End-Stage Liver Disease (MELD) ....

United Kingdom , End Stage Liver Disease , Landmark Trials , Classics Series , British Journal , Child Pugh , Chronic Liver Disease , Model For End Stage Liver Disease , General Medicine Classics , Surgery Classics , The Classics ,

The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]

1. The ABCD2 score is a validated, seven-point, risk-stratification tool to identify patients at high risk of stroke following a transient ischemic attack (TIA). 2. Patients with scores ≥4 are at considerably higher risk of stroke in the 2-day period following a TIA, and may potentially require urgent intervention as inpatients. Original Date of Publication: ....

United Kingdom , United States , Landmark Trials , Classics Series , Kaiser Permanente Medical Care Plan , Northern California , Emergency Classics , General Medicine Classics , The Classics ,