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"Gabapentin for Pain in Pediatric Palliative Care" by Ross Drake, Grace Prael et al.

Objective: Gabapentin is commonly used to treat pain in children receiving pediatric palliative care. This study describes the real-world use of gabapentin and the associated benefits and adverse effects/events (AEs). Methods: A prospective, multicenter cohort of standardized data collection after a clinical decision was made to use gabapentin for managing neuropathic or nociplastic pain in children attended on by a pediatric palliative care service. It was conducted across 11 sites in seven countries including hospital, inpatient, and outpatient services. Clinical outcomes were graded using pain scales validated for age and cognitive ability and the National Cancer Institute Common Terminology Criteria for Adverse Events (NCICTCAE) at baseline, 14 days, 28 days, six weeks and 12 weeks after initiation of gabapentin. Ad-hoc safety reporting continued throughout the study. Results: Data were collected from 127 children with a median age of 4.7 years (IQR 0.1–17.9); 61% had a neurologi ....

Lansky Karnofsky , Adverse Events , Pediatric Palliative Care , Quality Improvement ,

Charges against caretaker for deaths of infant girl, dog in hot car upgraded to murder

The caretaker arrested after an infant and a dog died in a hot car is back in jail and charged with murder.The York-Poquoson Sheriff’s Office in Virginia got ca ....

United States , Kristen Danielle Graham , York Poquoson Sheriff Office , York Poquoson Sheriff , Law Crime , Sheriffs In The United States , Law Enforcement In The United States , Child Neglect ,