Out isnt inevitable. So, how about the idea of being able to increase our health span live the better years of our life for longer, till, like, were a0 at 60. There is 15 17 years of healthy life that is up for grabs for all of us. We head to california to meet the scientists and founders who want to make it a reality. Ageing by itself is the largest risk factor for every single disease, this Chronic Disease of ageing, so by targeting it, you target all disease together. But how do we separate science from snake oil . The Longevity Industry is worth billions with hopes of delaying disease, extending our sprightly years and maybe even throwing in a few extra. I let a system of science and data run my body. It does a betterjob taking care of me than i can. Maybe even our Furry Friends can be with us for longer. He sneezed in my face. And the things some people will do to stay young push it out, push it out. You got this. Do you consider yourself a guinea pig . No, i dont i consider mysel
some real risk? certainly, there s always risks. but there s potentially an argument that we are being more safe than anyone else because we have the rigour of measurement. whilst bryan signed his life away to experimentation, i visit the buck, the world s first institute for ageing research. these scientists are working on drugs that they hope could delay age related disease. so, here, i have two of my postdocs, margie and genesis. would you say there has been huge scientific advancement in this field recently, or is there just a sudden trend for investment and interest in it? the science has matured in terms of, you know, we ve been doing this for close to 30 years, understanding the basic mechanism of ageing, number one. number two, the societal needs are there. you have a rapidly ageing population with an increasing burden of chronic diseases.
will not approve drugs just foranti ageing, companies are looking for a specific problem to treat. alzheimer s disease is an important one, cardiovascular diseases, kidney diseases, liver diseases all of these are diseases that are more prevalent as we get older and to the extent that they have a basis of cellular senescence, these agents we re working on could have applicability in other disease areas. what have you got here? that looks like it s connected to an eye? so, yeah, we get normal eyes and diseased eyes. we process them into this wax like substance, so that we can section the eye, a cross section of it very thinly and put it on a microscope slide. here we are testing different drug candidates on our animal models. so, we test, in a diseased animal model, does our drug actually inhibit or get rid of it once it is already formed?
i think brian is a true pioneer. is there not a bit of a risk in what he is doing to himself. there is a concern, we will see what happens to him in the long term. so far his numbers look good, he claims to be extremely happy, it s an interesting experiment for us to watch. delicious! the reality is we know a lot about the science of ageing. squeeze, squeeze, squeeze. but the big scientific breakthroughs just are not there yet, so i guess i come away from this feeling more than ever that it is so important to live your healthiest life, just maybe not quite to the extent of brianjohnson. lucky us, we exist. let s play the most fun games we can for as long as we can.
out isn t inevitable. so, how about the idea of being able to increase our health span live the better years of our life for longer, till, like, we re a0 at 60. there is 15 17 years of healthy life that is up for grabs for all of us. we head to california to meet the scientists and founders who want to make it a reality. ageing by itself is the largest risk factor for every single disease, this chronic disease of ageing, so by targeting it, you target all disease together. but how do we separate science from snake oil? the longevity industry is worth billions with hopes of delaying disease, extending our sprightly years and maybe even throwing in a few extra. i let a system of science and data run my body. it does a betterjob taking care of me than i can.