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New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients. ....

Giovanni Traverso , Nikhilb Lal , Louis Deridder , Jacquelinen Chu , Christopherm Colangelo , Robert Langer , Johanneslp Kuosmanen , Shriyas Srinivasan , Makaya Chilekwa , David Trumper , Josh Jenkins , Brianm Wolpin , Naomi Zecharias , Alisonm Hayward , Wiam Madani , Ameyar Kirtane , Keiko Ishida , Niora Fabian , Emmeline Macpherson , Aaron Lopes , Josh Morimoto , Troy Quast , Wei Huang , Nina Fitzgerald , Douglas Rubinson , Program In Health Sciences ,

The underutilized test that could prevent chemo overdosing

Discover how a simple genetic test could save lives by preventing chemotherapy drug overdoses, but only 3% of oncologists are routinely ordering it. ....

Dana Farber Cancer Institute , Health News , Veterans Affairs , A Cancer Network , Cancer Network , Boston Based Dana Farber Cancer Institute , Mayo Clinic , Genetic Test , Chemotherapy Drug , Ene Deficiency , Cancer Treatment Guidelines ,

Puffed-up MOFs show improved performance as drug-delivery vehicles

The spongelike structure of metal organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds. ....

United States , Fateme Rezaei , American Chemical Society , University Of Miami , Abio Materials , Drug Delivery ,

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival. ....

Peakstock Shutterstock , Image Credit , Colorectal Cancer , Fecal Microbiota Transplantation , Ell Death , Growth Factor , Programmed Cell Death ,

1 cancer drug in shortage nearing 100% resupply, White House says

The White House has announced that the shortage of cisplatin, a drug used to treat multiple types of cancer, is close to ending. ....

White House , District Of Columbia , United States , American Society Of Health , White House Office Of Science , Intas Pharmaceuticals , China Based Qilu Pharmaceutical , American Society , Health System Pharmacists , White House , Intas Pharmaceuticals , Cancer Centers ,