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ADCs and Immunotherapy Are Redefining Urothelial Cancer Treatment

Bupathi highlights key points that were presented at an OncLive Institutional Perspectives in Cancer, including implications of the EV-302 trial findings; data updates from the phase 1/2 ICRA trial; and future directions for urothelial cancer.

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Colorado
United-states
Manojkumar-bupathi
Mountain-cancer-centers-in-littleton
Institutional-perspectives
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Enfortumab-vedotin
Pembrolizumab
Urothelial-carcinoma
Targeted-therapy
Ev-302-trial-

FDA Approves Enfortumab Vedotin Plus Pembrolizumab for Locally Advanced or Metastatic Bladder Cancer

In the phase 3 EV-302/KEYNOTE-A39 clinical trial, the antibody-drug conjugate enfortumab vedotin plus PD-1 inhibitor pembrolizumab nearly doubled both median overall survival and progression-free survival compared with chemotherapy.

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United-kingdom
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Americans
Astellas-pharma
Ahsan-arozullah
Thomas-powles
European-society-for-medical-oncology-congress
Barts-cancer-centre-at-st
Olivier-le-moal
European-society

Enfortumab Vedotin and the Role of ADCs in Bladder Cancer

Bladder cancer specialists discuss enfortumab vedotin and the role of antibody-drug conjugates in the treatment landscape.

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Bladder-cancer
Non-muscle-invasive-bladder-cancer
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Nmibc-treatment
Bladder-cancer-treatment

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