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Hope that a cancer drug can stop FOP, one of the rarest diseases in the world


Hope that a cancer drug can stop FOP, one of the rarest diseases in the world
STOPFOP are trialling the cancer drug saracatinib, which has shown promise in stopping muscle and tissue from turning to bone in FOP patients 
The ACVR1 gene. Image by By Pleiotrope (public domain via Wikipedia )
 
Fibrodyplasia ossificans progressiva (FOP) is a rare and devastating disease in which muscles, tendons and ligaments slowly turn to bone. People with FOP gradually get ‘locked in’ their bodies, making it difficult to move and breathe. It’s caused by a mutation in a single gene, called ACVR1, which encodes for the protein kinase ALK2. The mutation causes ALK2 to become overactive, causing muscles and connective tissues to turn into bone. There is no drug to treat this disease. ....

United Kingdom , City Of , Noord Holland , Clemens Stockklausner , Alex Bullock , Marelise Eekhoff , University Of Oxford , Nuffield Department Of Clinical Medicine , Garmisch Partenkirchen Medical Center , Richard Keen , Royal National Orthopaedic Hospital , Nuffield Department , Clinical Medicine , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , நூற்த் ஹாலண்ட் , அலெக்ஸ் காளை மாடு , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , நுஃபையீல்ட் துறை ஆஃப் மருத்துவ மருந்து , ரிச்சர்ட் கீந் , அரச தேசிய எலும்பியல் மருத்துவமனை , நுஃபையீல்ட் துறை , மருத்துவ மருந்து ,

19 January 2021 Coronavirus Charts and News: UK Variant Has Been Circulating In The U.S. Since Early- to Mid-November. U.S. Not Doing Enough Genome Sequencing To Detect New Variants.


The U.S. new cases 7-day rolling average are 16.8 % LOWER than the 7-day rolling average one week ago. U.S. hospitalizations due to COVID-19 are now 2.8 %
LOWER than the rolling average one week ago. U.S. deaths due to coronavirus are now 3.3 %
LOWER than the rolling average one week ago. Today s posts include:
U.S. Coronavirus New Cases are 141,999 [likely understated due to the MLK holiday]
U.S. Coronavirus hospitalizations are at an elevated 123,848
U.S. Coronavirus deaths are 1,403 [likely understated due to the MLK holiday]
U.S. Coronavirus immunizations have been administered to 3.7 % of the population [not updated since 15 January] ....

New York , United States , University Of Arizona , United Arab Emirates , United Kingdom , South Africa , San Diego , Garmisch Partenkirchen , Los Angeles County , Clemens Stockklausner , Steven Hansen , Michael Worobey , Rachel Levine , Gustave Perna , Moderna Covid , Walter Ricciardi , Olivier Veran , David Aizuss , California Medical Association , Thermo Fisher , Emergency Management Agency , Washington Post , California Department Of Public Health , European Union , Paycheck Protection Program , Pennsylvania Health ,

Germany Extends Existing Lockdown Until February


Germany Extends Existing Lockdown Until February
Germany will extend its ongoing COVID-19lockdown measures until Feb. 14 amid fears of a new virus variant and continued attempts to bring infection rates down. The existing lockdown was supposed to expire at the end of this month.
German Chancellor Angela Merkel met with the country’s state leaders on Jan. 19, deciding to keep most “nonessential” businesses and schools closed.
Merkel told reporters after the meeting that Germany may consider closing its borders to neighboring countries that don’t take action to stop transmission of the CCP virus. The country shares borders with nine European nations. ....

South Africa , United Kingdom , Richland Hills , United States , South African , Clemens Stockklausner , Angela Merkel , Tom Pennington Getty , Johns Hopkins University , Public Health England , Chinese Communist Party , Chancellor Angela Merkel , Times Photo , Prestige Ameritech , Getty Images , Garmisch Partenkirchen Clinic , Johns Hopkins , Ccp Virus , Covid 19 , The Epoch Times , ஒன்றுபட்டது கிஂக்டம் , ரிச்லேண்ட் மலைகள் , ஒன்றுபட்டது மாநிலங்களில் , ஏஞ்சலா மர்கல் , டோம் பென்னிங்டன் கெட்டி , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் ,