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Dexpramipexole could be a promising treatment for eosinophilic asthma

Dexpramipexole could be a promising treatment for eosinophilic asthma
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United Kingdom , Salman Siddiqui , Knopp Biosciences , Calman Prussin , Severe Asthma Consortium Trials Program , National Institute For Health Research , Professor Of Airway Disease At Leicester University , International Conference , Vice President , Airway Disease , Leicester University , Asthma Consortium Trials Program , National Institute , Health Research , ஒன்றுபட்டது கிஂக்டம் , சல்மான் ஸிடீக்வி , க்னொபப் உயிர் அறிவியல் , தேசிய நிறுவனம் க்கு ஆரோக்கியம் ஆராய்ச்சி , சர்வதேச மாநாடு , துணை ப்ரெஸிடெஂட் , காற்று வாங்கி நோய் , லெய்செஸ்டர் பல்கலைக்கழகம் , தேசிய நிறுவனம் , ஆரோக்கியம் ஆராய்ச்சி ,

Knopp Biosciences Reports Positive Results From the Phase 2 EXHALE Trial of Oral Dexpramipexole in Moderate-to-Severe Eosinophilic Asthma at ATS 2021

Knopp Biosciences Reports Positive Results From the Phase 2 EXHALE Trial of Oral Dexpramipexole in Moderate-to-Severe Eosinophilic Asthma at ATS 2021
05/17/2021 | 06:01am EDT
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Dexpramipexole was well tolerated, with 97% of drug-treated patients completing the primary assessment phase
Knopp Biosciences LLC today announced detailed results of its positive Phase 2 dose-ranging EXHALE trial of the novel oral eosinophil-lowering drug dexpramipexole in patients with moderate-to-severe asthma. The data were presented in a virtual poster session at the ATS 2021 International Conference.
The EXHALE trial was a randomized, double-blind, placebo-controlled study of dexpramipexole in patients with moderate-to-severe asthma and blood absolute eosinophil count (AEC) ≥300/µL. Dexpramipexole study drug at oral doses of 75 mg/day, 150 mg/day, or 300 mg/day was added to standard of care. The primary endpoint was change in AEC from Baseline to Week ....

Knopp Biosciences , Calman Prussin , Drug Administration , American Partnership For Eosinophilic Disorders , International Conference , Global Initiative For Asthma , Global Initiative , Vice President , Translational Medicine , American Partnership , Eosinophilic Disorders , க்னொபப் உயிர் அறிவியல் , அமெரிக்கன் கூட்டு க்கு எயாஸிநொஃபிலிக் கோளாறுகள் , சர்வதேச மாநாடு , உலகளாவிய முயற்சி க்கு ஆஸ்துமா , உலகளாவிய முயற்சி , துணை ப்ரெஸிடெஂட் , மொழிபெயர்ப்பு மருந்து , அமெரிக்கன் கூட்டு , எயாஸிநொஃபிலிக் கோளாறுகள் ,

Knopp Biosciences LLC: Knopp Biosciences to Present Details of Positive Results From the Phase 2 EXHALE Trial of Oral Dexpramipexole in Moderate-to-Severe Eosinophilic Asthma at ATS 2021

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Poster presentation will describe effects of dexpramipexole on blood absolute eosinophil count, lung function, and safety
Knopp Biosciences LLC today announced it will present detailed results of its positive Phase 2 dose-ranging EXHALE trial of the novel oral eosinophil-lowering drug dexpramipexole in patients with moderate-to-severe asthma in a virtual poster session at the ATS 2021 International Conference.
We look forward to sharing comprehensive results of the EXHALE trial, which underscore the readiness of dexpramipexole for further development in eosinophilic asthma, said Michael Bozik, M.D., president and CEO of Knopp. Monoclonal antibody treatments approved for asthma demonstrate that reduction in eosinophils is associated with significantly improved outcomes, but the need remains for an oral alternative in the eosinophilic asthma treatment paradigm. ....

Michael Bozik , Kostenloser Wertpapierhandel , Tom Petzinger , Knopp Biosciences , Calman Prussin , Drug Administration , International Conference , Dexpramipexole Efficacy , Lowering Blood Eosinophils , Severe Uncontrolled Eosinophilic Asthma , Translational Medicine , மைக்கேல் போசிக் , டோம் பெட்ஸிங்கர் , க்னொபப் உயிர் அறிவியல் , சர்வதேச மாநாடு , மொழிபெயர்ப்பு மருந்து ,