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Novel Method Yields Unique Anticancer Molecules by Chemists

Novel Method Yields Unique Anticancer Molecules by Chemists
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Yale chemists create novel anticancer molecules

Yale chemists synthesize complex anticancer molecules from marine invertebrates

Nearly 30 years ago, scientists discovered a unique class of anticancer molecules in a family of bryozoans, a phylum of marine invertebrates found in tropical waters.

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Chemists synthesize unique anticancer molecules using novel approach

Chemists synthesize unique anticancer molecules using novel approach
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National-science-foundation

Yale chemists synthesize unique anticancer mo

<p>Nearly 30 years ago, scientists discovered a unique class of anticancer molecules in a family of bryozoans, a phylum of marine invertebrates found in tropical waters.</p> <p>The chemical structures of these molecules, which consist of a dense, highly complex knot of oxidized rings and nitrogen atoms, has attracted the interest of organic chemists worldwide, who aimed to recreate these structures from scratch in the laboratory. However, despite considerable effort, it has remained an elusive task. Until now, that is.</p> <p>A team of Yale chemists, writing in the journal Science, has succeeded in synthesizing eight of the compounds for the first time using an approach that combines inventive chemical strategy with the latest technology in small molecule structure determination.</p>

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Department-of-chemistry
National-science-foundation
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