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Subgroup Observations From Missed KEYNOTE-789 Data in NSCLC Provide Insight for the Future

James Chih-Hsin Yang, MD, PhD, discusses the implications of the phase 3 KEYNOTE-789 trial and what directions investigators can examine in the future to help fill the unmet need for patients with TKI-resistant, EGFR-mutated metastatic non–small cell lung cancer.

James-chih-hsin-yang
Department-of-oncology
Institute-of-oncology
National-taiwan-university
National-taiwan-university-hospital
Graduate-institute
East-asian
Keynote-789
Nsclc
Non-small-cell-lung-cancer
Lung-cancer
Pembrolizumab

PRGN-2009 Plus Bintrafusp Alfa Shows Early Activity in HPV-Associated Malignancies

James L. Gulley, MD, PhD, reviews the safety and efficacy of PRGN-2009 alone and in combination with bintrafusp alfa in HPV-associated cancers and explains how this kind of approach may address an unmet clinical need.

Maryland
United-states
Jamesl-gulley
Cancer-research
National-cancer-institute
Prgn-2009
Bintrafusp-alfa
Hpv-associated-malignancies
Pasco
Asco-annual-meeting

CAR T-Cell Therapy in Metastatic CRPC and Future Directions in Care

Closing out their final module, expert panelists consider the role of CAR T-cell therapy in metastatic castration-resistant prostate cancer and look toward future evolutions in the broader treatment landscape.

Treatment-approaches
Prostate-cancer
Cell-therapy
Future-directions
Metastatic-prostate-cancer
Nmcrpc
Castration-resistant-prostate-cancer
Cart-therapy
Cart-cell-therapyt-bispecifics
Bispecific-therapy
Clinical-trials

Sunvozertinib Approved in China for NSCLC With EGFR Exon 20 Insertion Mutations

The National Medical Products Administration of China has approved sunvozertinib for use in adult patients with locally advanced or metastatic non–small cell lung cancer harboring EGFR exon 20 insertion mutations whose disease has progressed on or following platinum-based chemotherapy.

China
Peking
Beijing
Mengzhao-wang
Xiaolin-zhang
National-medical-products-administration-of-china
Union-medical-college-hospital
National-medical-products-administration
Peking-union-medical-college-hospital
Sunvozertinib
Nsclc
Non-small-cell-lung-cancer

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