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Prostate-specific antigen screening more cost effective than first-line MRI

First-line prostate-specific antigen testing with second-line multiparametric MRI was a more cost effective screening strategy for prostate cancer than biparametric MRI as a first-line approach, a study showed.Prior research has tied prostate-specific antigen (PSA) screening for prostate cancer with high rates of overdiagnoses and limited reductions in cancer-specific mortality, Roman Gulati, MS,

Circumcision prevents HIV among men who have sex with men

Voluntary medical male circumcision was effective in preventing HIV infection among men who have sex with men, or MSM, according to a randomized controlled trial recently published in Annals of Internal Medicine.The CDC estimates that one in six MSM will develop HIV infection in their lifetime compared with one in 524 heterosexual men and one in 253 heterosexual women.

Low testosterone tied to increased risk for mortality, CVD events

Men with low testosterone concentrations had a higher risk for all-cause mortality, and those with very low testosterone also had an increased risk for CVD mortality, a study in Annals of Internal Medicine showed.“Given the effects of testosterone on male libido, virilization, and body composition . an important question has been whether and when lower endogenous testosterone

Drugs to help adults stop vaping … and other research

Tom Nolan reviews this week’s research Over the past year we’ve seen various trials that assess vaping as an intervention for smoking cessation. Now we have smoking cessation drugs being studied as interventions to help people stop vaping. Cytisinicline, a plant based alkaloid that targets nicotinic acetylcholine receptors, has been available in the UK since the start of this year. One hundred and sixty non-smokers who use nicotine vapes were randomised to either cytisinicline 3 mg three times a day for 12 weeks or placebo (both groups received behavioural support). Participants were asked to set a quit date seven to 14 days after the start of treatment. Some 31.8% of those in the cytisinicline group, and 15.1% in the placebo group had stopped vaping between nine and 12 weeks (odds ratio, 2.64; 95% CI, 1.06 to 7.10). However, by 16 weeks the gap between the groups had …

Significant and Sustained Improvements in Renal Function Reported for Adults with Chronic Hypoparathyroidism Treated with TransCon™ PTH (Palopegteripa