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Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome

Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome
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United States , Dejan Juric , Bryan Corcoran , Andreas Varkaris , Termeer Center , Cancer Center , Gastrointestinal Cancer Center , Therapies Investigational Cancer Therapeutics Program , Cancer Discovery , Mass General Cancer Center , Mass General Brigham , Ferran Fece De La Cruz , Mass General Cancer , Targeted Therapy , Targeted Therapies , Investigational Cancer Therapeutics Program , Scientific Director ,

TransCode Therapeutics Announces Preliminary Clinical Results in First Patient in Phase 0 Clinical Study with Lead Therapeutic Candidate, TTX-MC138

TransCode Therapeutics Announces Preliminary Clinical Results in First Patient in Phase 0 Clinical Study with Lead Therapeutic Candidate, TTX-MC138
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United States , Zdravka Medarova , Andreas Varkaris , Michael Dudley , Alan Freidman , Transcode Therapeutics Inc , Exchange Commission , Termeer Center , First Patient , Lead Therapeutic Candidate , Code Therapeutics , Drug Metabolism , Chief Technology Officer , Chief Executive Officer , Targeted Therapies , Massachusetts General Hospital , Private Securities Litigation Reform Act , Investigational New Drug , Annual Report ,

TransCode Therapeutics (RNAZ) Announces Preliminary Clinical Results in First Patient in Phase 0 Clinical Study with Lead Therapeutic Candidate, TTX-MC138

TransCode Therapeutics (RNAZ) Announces Preliminary Clinical Results in First Patient in Phase 0 Clinical Study with Lead Therapeutic Candidate, TTX-MC138
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United States , Andreas Varkaris , Michael Dudley , Zdravka Medarova , Termeer Center , Transcode Therapeutics Inc , Transcode Therapeutics , Drug Metabolism , Chief Technology Officer , Chief Executive Officer , Targeted Therapies , Massachusetts General Hospital ,

Community and Cancer at Center of AFC Fourth Anniversary. What was it like to be there? – Dielli

Community and Cancer at Center of AFC Fourth Anniversary. What was it like to be there? – Dielli
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United States , Blue Hill Country Club , New York , Roberta Panariti , Brizida Koci , Enkela Pance , Agim Aliaj , Rafaela Prifti , Andreas Varkaris , Albanab Mihali , Irvin Cepa , Zhenisa Hysenaj , Albana Mihali , Lorenc Malellari , Harvard Cancer Center , Robotic Surgical Center , Clinical Committee , Health Insurance Policy Leader , Ivi Kasimati , Colon Cancer , Breast Cancer , New Treatments , Clinical Trials , Clinical Committee Chair , Board Certified , General Surgery ,

RLY-2608 Shows Broad Therapeutic Potential in PIK3CA-Mutant Solid Tumors

RLY-2608 led to sustained target inhibition with minimal effect on glucose homeostasis, acceptable safety, and antitumor activity in patients with PIK3CA-mutant solid tumors, according to interim data from the dose-escalation portion of the first-in-human phase 1 ReDiscover trial. ....

United States , Andreas Varkaris , Massachusetts General Hospital , First In Human Phase 1 Rediscover Trial , 2023 Aacr Annual Meeting , Rly 2608 , Patients With Pik3ca Mutant Solid Tumors ,