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NK cells' role in cancer therapy resistance unveiled

Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. ....

Baden Wüberg , Michael Kilian , Michael Platten , Head Of Department , University Medical Center Mannheim , German Cancer Research Center , Heidelberg University Hospital , German Cancer Research Center Deutsches Krebsforschungszentrum , Department Of Haematology , Neurological University Clinic Mannheim , Cancer Research Center , Deutsches Krebsforschungszentrum , Neurological University Clinic , Ancer Immunotherapy , Cancer Prevention , Immune System , Natural Killer Cells ,

Merck and Bristol-Myers Squibb brace for loss of lucrative drug patents

New quarterly earnings reports offer insight into how the companies are preparing to potentially lose significant sources of revenue ....

Bristol Myers Squibb , Christophers Boerner , Robertm Davis , Wall Street , Harpoon Therapeutics , Aqua Business , Bristol Myers Squibb , Bristol Myers , Christophers Boerner , Merck Amp Co , Orphan Drugs , Antineoplastic Drugs , Schering Plough , Pharmaceutical Industry , Harpoon Therapeutics , Ancer Immunotherapy , Robertm Davis ,

Siblings with unique gene mutation offer insights into type 1 diabetes treatment

Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress the search for new treatments in type 1 diabetes. ....

Rockefeller University , New York , United States , United Kingdom , City Of , North Yorkshire , Masato Ogishi , Ben Williams , Matthew Johnson , Rockefeller Institute , Us National Institutes For Health , Harryb Helmsley Charitable , Exeter Biomedical Research Centre , King College London , Helmsley Program , University Of Exeter , National Institute Of Health , Exeter Clinical Research Facility , Care Research , Experimental Medicine , Study Author , College London , Charitable Trust , Diabetes United Kingdom , Professor Timothy Tree , Lucy Chambers ,

New immunotherapy target activin receptor 1C shows promise against cancer

Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients' immune systems fight back against cancer, according to a study by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. ....

Xiaoxu Wang , Ying Zheng , Nicolasj Llosa , Johns Hopkins , Andrea Otrocol , Juan Fu , Chong Yu , Jelanic Zarif , Andriana Lebid , University School Of Medicine , Johns Hopkins University , Johns Hopkins Kimmel Cancer Center , Johns Hopkins University School Of Medicine , Bloomberg Kimmel Institute For Cancer Immunotherapy , Kimmel Institute , University School , Immunomic Therapeutics , Liam Chung , Johns Hopkins University School , Ancer Immunotherapy , Immune System ,

Aging alters fibroblasts to promote pancreatic cancer growth

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and the Bloomberg~Kimmel Institute for Cancer Immunotherapy. ....

United States , Fox Chase Cancer Center , Baden Wüberg , Stanford School , National Institutes Of Health , Johns Hopkins University , Toddd Armstrong , Samantha Guinn , Sneha Pramod , Johns Hopkins , Yash Chhabra , Elizabeth Jaffee , Jacquelynw Zimmerman , Jamesl Leatherman , Soren Charmsaz , Ashani Weeraratna , Emma Kartalia , Mitchelle Fane , Daniel Zabransky , Elizabethd Thompson , Metastasis Program , Bloomberg Kimmel Institute For Cancer Immunotherapy , National Institute On Aging In Baltimore , Parker Institute , German Cancer Research Center , University Medical Center Mannheim ,