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Adjuvant everolimus does not improve survival for patients with resected renal cell carcinoma

1. Recurrence-free survival was significantly different between the adjuvant everolimus and placebo groups. 2. Grade 3 or higher adverse events were more frequent in the everolimus group with oral mucositis being the most reported within this treatment arm. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with renal cell carcinoma face a high risk of ....

United States , Rating Level , Advanced Renal Cell , Between Apr , Immune Checkpoint Inhibitors , Kidney Cancer , Metastatic Renal Cell Carcinoma , Renal Cell Carcinoma , Tyrosine Kinase Inhibitor , Chronic Disease ,

Merck Announces First Positive Phase 3 Results For WELIREG From LITESPARK-005

Merck (MRK) announced topline results from LITESPARK-005, a Phase 3 trial investigating WELIREG, Merck's oral hypoxia-inducible factor-2 alpha inhibitor, in certain previously treated patients with Advanced Renal Cell Carcinoma. ....

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