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Team systematically modifies glyceraldehyde derivative JX22 for improved anti-heart failure efficacy and safety

Team systematically modifies glyceraldehyde derivative JX22 for improved anti-heart failure efficacy and safety
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Xiao Li , Acta Materia Medica ,

Efficient intranasal delivery of agomelatine via micellar encapsulation

Announcing a new publication for Acta Materia Medica journal. Agomelatine (AGO) is an antidepressant with limited clinical application due to its low bioavailability caused by poor water solubility, severe hepatic degradation, and poor intracerebral distribution. ....

Compuscript Ltd , Acta Materia Medica , Drug Delivery ,

Decoding the genetic links between diabetes, hyperlipidemia, and IBD

Announcing a new publication for Acta Materia Medica journal. Previous epidemiologic studies have shown a close association between type 1 diabetes mellitus (T1DM), hyperlipidemia, and inflammatory bowel disease (IBD), but the causal relationship has not been established. ....

Compuscript Ltd , Acta Materia Medica , Diabetes Mellitus , Inflammatory Bowel Disease , Type 1 Diabetes ,

Comprehensive analysis of immune checkpoint inhibitors reveals endocrine toxicity patterns

Announcing a new publication for Acta Materia Medica journal. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but pose a challenge of immune-related adverse events (irAEs), particularly endocrine toxicity, that can severely compromise patient well-being. ....

Compuscript Ltd , Acta Materia Medica , Cancer Treatment , Ell Death , Programmed Cell Death ,

Microbial decoration enhances drug delivery specificity and safety

Announcing a new publication for Acta Materia Medica journal. Microorganisms are mostly distributed on the surface of our skin and intestines and have crucial roles in physiologic and metabolic processes, such as digestion and immunity, which are closely related to diseases. ....

Compuscript Ltd , Acta Materia Medica , Drug Delivery ,