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Researchers make 'bombshell' discovery of an entirely new kind of biomolecule

Date Time
Researchers make ‘bombshell’ discovery of an entirely new kind of biomolecule
A newfound biomolecule, consisting of RNA modified by sugars, could be present in all forms of life and might contribute to autoimmune disease.
By Holly Alyssa MacCormick
Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.
The novel biomolecule, dubbed glycoRNA, is a small ribbon of ribonucleic acid (RNA) with sugar molecules, called glycans, dangling from it. Up until now, the only kinds of similarly sugar-decorated biomolecules known to science were fats (lipids) and proteins. These glycolipids and glycoproteins appear ubiquitously in and on animal, plant and microbial cells, contributing to a wide range of processes essential for life. ....

United States , Stacy Malaker , Benson George , Kayvon Pedram , Holly Alyssa Maccormick , Alex Johnson , Karim Majzoub , Jan Carette , Stanford Bio , Howard Chang , Ryan Flynn , Carolyn Bertozzi , Stanford School Of Humanities , National Cancer Institute , National Science Foundation , Department Of Stem Cell , Damon Runyon Cancer Research , Dk Ludwig Professor Of Cancer Research , Cancer Research Of The United States , Maternal Child Health Research Institute , National Institute , Stanford Wu Tsai Neurosciences Institute , Yale University , Stanford Chemistry Biology Interface Predoctoral Training Program , National Institutes Of Health , Medicine For Human Health ,

Stanford study reveals new biomolecule

A newfound biomolecule, consisting of RNA modified by sugars, could be present in all forms of life and might contribute to autoimmune disease. ....

United States , Stacy Malaker , Benson George , Kayvon Pedram , Alex Johnson , Karim Majzoub , Jan Carette , Stanford Bio , Howard Chang , Ryan Flynn , Carolyn Bertozzi , Stanford School Of Humanities , National Cancer Institute , National Science Foundation , Department Of Stem Cell , Damon Runyon Cancer Research , Dk Ludwig Professor Of Cancer Research , Cancer Research Of The United States , Maternal Child Health Research Institute , National Institute , Stanford Wu Tsai Neurosciences Institute , Yale University , Stanford Chemistry Biology Interface Predoctoral Training Program , National Institutes Of Health , Medicine For Human Health , Stanford Cancer Institute ,

Stanford researchers use AI to empower environmental regulators

Brick kilns have proliferated across Bangladesh to supply the growing economy with construction materials, which makes it really hard for regulators to keep up with new kilns that are constructed, said co-lead author Nina Brooks, a postdoctoral associate at the University of Minnesota s Institute for Social Research and Data Innovation who did the research while a PhD student at Stanford.
While previous research has shown the potential to use machine learning and satellite observations for environmental regulation, most studies have focused on wealthy countries with dependable data on industrial locations and activities. To explore the feasibility in developing countries, the Stanford-led research focused on Bangladesh, where government regulators struggle to locate highly pollutive informal brick kilns, let alone enforce rules. ....

New York , United States , Jihyeon Lee , David Lobell , Debashish Biswas , Fahim Tajwar , Richard Kushel , Marshall Burke , Stanford Bio , Stephen Luby , Stanford King Center , Global Development , Stanford School Of Medicine , National Science Foundation , Center On Food Security , Stanford School Of Earth , Artificial Intelligence Lab , Stanford School Of Engineering , University Of Minnesota Institute For Social Research , Stanford Woods Institute For The Environment , Stanford Institute For Economic Policy Research , Freeman Spogli Institute For International , Energy Environmental Sciences Stanford Earth , Proceedings Of The National Academy Sciences , International Centre For Diarrheal Disease Research , Stanford Maternal Child Health Research Institute ,

Researchers use AI to empower environmental regulators

Researchers use AI to empower environmental regulators
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New York , United States , Jihyeon Lee , David Lobell , Debashish Biswas , Fahim Tajwar , Richard Kushel , Marshall Burke , Stanford Bio , Stephen Luby , Stanford School Of Medicine , Stanford Woods Institute For The Environment , University Of Minnesota Institute For Social Research , National Science Foundation , Freeman Spogli Institute For International , Stanford Institute For Economic Policy Research , Center On Food Security , Proceedings Of The National Academy Sciences , Energy Environmental Sciences Stanford Earth , Stanford King Center On Global Development , Stanford School Of Earth , International Centre For Diarrheal Disease Research , Artificial Intelligence Lab , Stanford School Of Engineering , Stanford Maternal Child Health Research Institute , Stanford University Led ,

Single-dose COVID-19 vaccine triggers antibody response in mice

ACS Central Science
Across the world, health care workers and high-risk groups are beginning to receive COVID-19 vaccines, offering hope for a return to normalcy amidst the pandemic. However, the vaccines authorized for emergency use in the U.S. require two doses to be effective, which can create problems with logistics and compliance. Now, researchers reporting in ACS Central Science have developed a nanoparticle vaccine that elicits a virus-neutralizing antibody response in mice after only a single dose.
The primary target for COVID-19 vaccines is the spike protein, which is necessary for SARS-CoV-2’s entry into cells. Both of the vaccines currently authorized in the U.S. are mRNA vaccines that cause human cells to temporarily produce the spike protein, triggering an immune response and antibody production. Peter Kim and colleagues wanted to try a different approach: a vaccine consisting of multiple copies of the spike protein displayed on ferritin nanoparticles. Ferri ....

United States , Chan Zuckerberg Biohub , Frank Quattrone , Peter Kim , Us Congress , Damon Runyon Cancer Research Foundation , Denise Foderaro Family Research Fund , National Institutes Of Health , Dk Ludwig Fund For Cancer Research , American Chemical Society , Stanford Maternal Child Health Research Institute , Stanford Maternal , Child Health Research Institute , National Institutes , Ludwig Fund , Cancer Research , Denise Foderaro Family Research , ஒன்றுபட்டது மாநிலங்களில் , பீட்டர் கிம் , எங்களுக்கு காங்கிரஸ் , டாமன் றுஞயோன் புற்றுநோய் ஆராய்ச்சி அடித்தளம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , ட்கே லுட்விக் நிதி க்கு புற்றுநோய் ஆராய்ச்சி , அமெரிக்கன் இரசாயன சமூகம் , ஸ்டான்போர்ட் தாய்வழி குழந்தை ஆரோக்கியம் ஆராய்ச்சி நிறுவனம் , ஸ்டான்போர்ட் தாய்வழி ,