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Novartis study: Nurses and MS patients give thumbs-up to Kesimpta for ease of use


Mar 3, 2021 9:55am
Novartis presented positive study data at the sixth annual Americas Committee for Treatment and Research in Multiple Sclerosis Forum from nurses and patients using its Kesimpta auto-injector pen for MS. (Novartis)
Novartis nabbed FDA approval for Kesimpta to treat multiple sclerosis last year, but now it’s getting the thumbs-up from MS patients and nurses.
Novartis presented study data at the sixth annual Americas Committee for Treatment and Research in Multiple Sclerosis Forum in late February showing 84% preferred Kesimpta’s self-administration injector pen over rival administration methods.
The kudos from a small, 130-participant study come as Novartis bids to make Kesimpta a first-treatment option. Kesimpta’s chief rival Roche’s Ocrevus, which also works by targeting CD20-expressing B-cells is an infusion treatment. ....

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Roche is gearing up to knock down an Irish plant—and it's complicated


Mar 4, 2021 11:33am
Roche decided in 2015 to close four small-molecule manufacturing plants around the world. It found buyers for three. But the one that the company couldn t sell was in Clarecastle, Ireland. Destruction of the facility begins in June. (Roche)
Unable to sell its plant in Clarecastle, Ireland, Roche will take a wrecking ball to the facility in June.
It won’t be a simple process. In fact, a timeline of June 2021 to May 2028 has been listed for the project, which requires removing 10 buildings and infrastructure from the 88-acre site. 
The most painstaking aspect of the operation will be recovery and removal of what lies underneath: Nearly 40,000 metric tons of waste has been identified on the property. And the project will require more than 90,000 metric tons of backfill to patch up the land afterward.  ....

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Merugikan Relawan, 5 Kasus Uji Klinis yang Berakhir Gagal

Merugikan Relawan, 5 Kasus Uji Klinis yang Berakhir Gagal
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Dear Dr. Roach: Crohn's disease caused narrowing of colon but no symptoms

DEAR DR. ROACH: I am a 77-year-old man in good health. I was diagnosed with Crohn s disease about 15 years ago, but had no symptoms. Recently I had a colonoscopy ....

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Kevin Durant out until after All-Star break with hamstring injury


PHOTO: AP
NEW YORK Kevin Durant will be out through the All-Star break because of a hamstring injury, sidelining the Brooklyn Nets star from a game for which he was chosen to serve as a captain.
The Nets said on Friday (Saturday, Manila time) that after a routine follow-up MRI on Durant s left hamstring, it was determined that he needed additional recovery time.
Durant has missed Brooklyn s last six games. The Nets, who have won eight straight, have three more games before the break.
Durant, in his first season back after recovering from surgery to repair a ruptured Achilles tendon, was the leading vote-getter in the Eastern Conference. That made him a captain of one of the teams in the March 7 All-Star Game, and he s scheduled to select a team opposite LeBron James next Thursday. ....

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